The Science Behind Proper No.1
Every ingredient is clinically studied and precisely dosed. No proprietary blends, no fairy-dusting—just transparent, evidence-based formulations.
Understanding Each Ingredient
Click on each ingredient to explore the science, benefits, and common myths.
The Most Researched Supplement in History
Creapure® Creatine
What is it?
Creatine is a naturally occurring compound found in muscle cells. It helps produce ATP, the primary energy currency of your cells. While your body makes about 1-2g daily, supplementation ensures optimal levels for peak performance and cognitive function.
Why It Matters for Women
For decades, creatine was marketed to men, but research shows women may benefit even more. Women have 70-80% lower natural creatine stores than men, making supplementation particularly impactful. Studies show women experience greater relative improvements in strength, cognitive function, and mood.
Key Benefits
Brain Health & Cognition
Improves memory, mental clarity, and cognitive performance—especially under stress.
Strength & Lean Muscle
Women see 20-25% greater strength gains when combining creatine with resistance training.
Hormonal Support
Helps offset hormonal impacts on energy, mood, and muscle during cycles and menopause.
Mood & Mental Health
May enhance antidepressant effectiveness and support mental wellbeing.
Myth vs. Reality
"Creatine causes bloating"
Water retention occurs inside muscle cells, creating a toned look—not subcutaneous bloating.
"Creatine is only for bodybuilders"
Benefits extend to cognitive health, aging, and everyday energy for all women.
"Women shouldn't take creatine"
Women may benefit MORE than men due to lower natural stores.
Hear From the Experts
Watch leading scientists and researchers explain the science behind our ingredients.
Explore the Published Research
Dive into the peer-reviewed clinical studies and research papers that back every ingredient in Proper No.1.
View All Studies